Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | PRNP | P04156 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115569 | 0.88 | KDM4E (0.50) | MAPTTP53LMNAKMT2AALDH1A1 | |
| SCHEMBL28115475 | 0.88 | MAPT (0.45) | RXFP1MAPTTP53LMNAPOLB | |
| SCHEMBL28837021 | 0.87 | MAPT (0.60) | MAPTTP53LMNANPSR1KMT2A | |
| SCHEMBL28115022 | 0.86 | DHODH (0.53) | MAPTTP53CA12CA1CA2 | |
| SCHEMBL28115074 | 0.86 | DHODH (0.54) | MAPTNPSR1PRNPKMT2AMEN1 | |
| SCHEMBL28837077 | 0.84 | TRPV1 (0.43) | MAPTLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL28115083 | 0.84 | MAPT (0.48) | MAPTTP53LMNAALDH1A1KDM4E | |
| SCHEMBL28115474 | 0.81 | MAPT (0.60) | MAPTTP53LMNAKMT2AMEN1 | |
| SCHEMBL28115476 | 0.76 | POLB (0.57) | MAPTTP53LMNAKMT2AMEN1 | |
| SCHEMBL28115023 | 0.76 | MAPT (0.46) | MAPTLMNANPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220560-A | A kind of preparation method of poly-substituted quinoline derivant | 华侨大学 | 2016-12-14 | — | — | CN | disclosed |