Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115569 | 0.92 | KDM4E (0.50) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28837021 | 0.91 | MAPT (0.60) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL26649487 | 0.84 | PDE10A (0.63) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28115476 | 0.82 | POLB (0.57) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28115475 | 0.82 | MAPT (0.45) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL26649418 | 0.81 | PDE10A (0.57) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28115074 | 0.81 | DHODH (0.54) | MAPTKDM4EALDH1A1L3MBTL1KMT2A | |
| SCHEMBL28115477 | 0.81 | RXFP1 (0.52) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28115022 | 0.81 | DHODH (0.53) | MAPTTP53KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28115083 | 0.80 | MAPT (0.48) | MAPTTP53KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220560-A | A kind of preparation method of poly-substituted quinoline derivant | 华侨大学 | 2016-12-14 | — | — | CN | disclosed |