Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115569 | 0.88 | KDM4E (0.50) | DHODHACACAALDH1A1HPGDCYP2C9 | |
| SCHEMBL28837021 | 0.87 | MAPT (0.60) | DHODHALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL28115074 | 0.86 | DHODH (0.54) | DHODHALDH1A1HPGDMAPK1MAPT | |
| SCHEMBL28115477 | 0.86 | RXFP1 (0.52) | ALDH1A1HPGDCYP2C9MAPTTP53 | |
| SCHEMBL28115083 | 0.84 | MAPT (0.48) | DHODHALDH1A1HPGDALOX5HSD17B10 | |
| SCHEMBL28837077 | 0.84 | TRPV1 (0.43) | DHODHALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL28115023 | 0.81 | MAPT (0.46) | DHODHACACAALDH1A1CYP2C9MAPT | |
| SCHEMBL28115474 | 0.81 | MAPT (0.60) | ALDH1A1HPGDHSD17B10MAPK1MAPT | |
| SCHEMBL28115475 | 0.79 | MAPT (0.45) | DHODHACACAALDH1A1HPGDCYP2C9 | |
| SCHEMBL28115476 | 0.76 | POLB (0.57) | ACACAALDH1A1HPGDMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220560-A | A kind of preparation method of poly-substituted quinoline derivant | 华侨大学 | 2016-12-14 | — | — | CN | disclosed |