Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115078 | 0.85 | LMNA (0.65) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL28115077 | 0.77 | KMT2A (0.68) | ALDH1A1KDM4EUSP2KMT2ALMNA | |
| SCHEMBL28115079 | 0.77 | KMT2A (0.68) | ALDH1A1USP2KMT2ALMNAMEN1 | |
| SCHEMBL8635324 | 0.75 | LMNA (0.59) | ALDH1A1KDM4EUSP2KMT2ALMNA | |
| SCHEMBL27837743 | 0.74 | LMNA (0.64) | ALDH1A1KDM4EUSP2ALOX15KMT2A | |
| SCHEMBL28805316 | 0.73 | L3MBTL1 (0.53) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL13195186 | 0.73 | ALDH1A1 (0.67) | ALDH1A1KDM4EUSP2KMT2ALMNA | |
| SCHEMBL27997536 | 0.73 | L3MBTL1 (0.71) | ALDH1A1KDM4EUSP2KMT2ALMNA | |
| SCHEMBL11607645 | 0.73 | KDM4E (0.56) | ALDH1A1KDM4EUSP2ALOX15NPSR1 | |
| SCHEMBL837646 | 0.73 | LMNA (0.64) | ALDH1A1KDM4EUSP2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146490-A | 5-hydroxyl-1,7-naphthyridine compounds, its preparation method and the pharmaceutical applications thereof replaced by aryloxy group or heteroaryloxy | 沈阳三生制药有限责任公司 | 2016-11-23 | — | — | CN | disclosed |