Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115226 | 0.83 | ALKBH5 (0.46) | EGFRSRCABCB1CXCR3SMN1; SMN2 | |
| SCHEMBL4106684 | 0.72 | EGFR (0.68) | EGFRSRCSMN1; SMN2NPC1MAPT | |
| SCHEMBL16414537 | 0.70 | GABRA1 (0.54) | SMN1; SMN2MAPTLMNATSHRGABRA1 | |
| SCHEMBL15730224 | 0.69 | BRD4 (0.53) | ABCB1SMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL13105884 | 0.68 | GABRA1 (0.46) | SMN1; SMN2ALDH1A1LMNATSHRHTT | |
| SCHEMBL11702583 | 0.67 | ALKBH5 (0.59) | SMN1; SMN2MAPTALDH1A1LMNATSHR | |
| SCHEMBL22450932 | 0.66 | MAPT (0.48) | EGFRSRCSMN1; SMN2NPC1MAPT | |
| SCHEMBL5451167 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1ALDH1A1LMNATSHR | |
| SCHEMBL17176451 | 0.65 | HTR3A (0.56) | EGFRSRCSMN1; SMN2NPC1MAPT | |
| SCHEMBL14864227 | 0.65 | THRB (0.50) | SMN1; SMN2MAPTLMNATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001220-B | Preparation method of indoloquinoline alkaloid analogues | 渤海大学 | 2017-01-11 | — | — | CN | disclosed |