SCHEMBL1666830

SCHEMBL1666830

Cc1cccc(-c2cc3ccc4c(N)ccc5ccc(c2N)c3c54)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.39
USP2 O75604 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
ADORA1 P30542 2/20 0.39
LRRK2 Q5S007 2/20 0.39
MAP4K4 O95819 2/20 0.39
CHEK1 O14757 1/20 0.39
ABL1 P00519 1/20 0.39
NTRK1 P04629 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
CSF1R P07333 1/20 0.39
MET P08581 1/20 0.39
PDGFRB P09619 1/20 0.39
PIM1 P11309 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29444827 1.00 MAOB (0.40) MAOBRAB9AKMT2AL3MBTL1MEN1
SCHEMBL28070710 0.87 ALDH1A1 (0.34) MAOBKMT2AL3MBTL1MEN1USP2
SCHEMBL28982412 0.84 KEAP1 (0.38) RAB9AKMT2AMEN1USP2KEAP1
SCHEMBL22589048 0.84 MEN1 (0.39) MAOBRAB9AKMT2AL3MBTL1MEN1
SCHEMBL28188087 0.83 ALDH1A1 (0.38) MAOBRAB9AKMT2AMEN1USP2
SCHEMBL28115335 0.83 ALDH1A1 (0.38) MAOBRAB9AKMT2AMEN1USP2
SCHEMBL29444822 0.81 ALDH1A1 (0.38) KMT2AL3MBTL1MEN1USP2ADORA1
M-Xylene SCHEMBL28369108 0.81 ACHE (0.48) RAB9AKMT2AL3MBTL1MEN1USP2
SCHEMBL28680640 0.81 DHFR (0.36) KMT2AMEN1USP2KEAP1NFE2L2
SCHEMBL28023770 0.81 NOS1 (0.40) KEAP1NFE2L2CHEK1FGFR1CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112441931-A Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus 株式会社半导体能源研究所 2021-03-05 CN disclosed
CN-110891936-A Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2020-03-17 CN disclosed
EP-2314565-B1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LAB (JP) 2013-07-24 EP disclosed
EP-2314565-A1 Fluorene Derivative, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-27 EP disclosed