Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23587249 | 0.80 | PARP10 (0.43) | METAP1ACHEPARP1PARP10ADORA1 | |
| SCHEMBL9629516 | 0.78 | METAP1 (0.41) | METAP1ACHEPARP1PARP10ADORA1 | |
| SCHEMBL30933590 | 0.78 | METAP1 (0.41) | METAP1ACHEPARP1PARP10ADORA1 | |
| SCHEMBL2972545 | 0.75 | TDP1 (0.38) | METAP1PARP1PARP10 | |
| SCHEMBL28115384 | 0.75 | METAP1 (0.39) | METAP1ACHEPARP1PARP10ADORA1 | |
| SCHEMBL8344964 | 0.72 | METAP1 (0.53) | METAP1ACHEPARP1PARP10ADORA1 | |
| SCHEMBL30057710 | 0.69 | HTR6 (0.40) | ACHEPARP1PARP10MAOAMAOB | |
| SCHEMBL21694409 | 0.69 | HTR6 (0.40) | ACHEPARP1PARP10MAOAMAOB | |
| SCHEMBL20219239 | 0.68 | HTR7 (0.39) | METAP1ACHEPARP1PARP10ADORA1 | |
| SCHEMBL11768880 | 0.68 | HTR7 (0.49) | METAP1ACHEPARP1PARP10ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349150-A | Method for synthesizing indene (1,2-b) indole-10(5H)-ketone compounds | 河南师范大学 | 2017-01-25 | — | — | CN | disclosed |