Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354288 | 0.83 | METAP1 (0.39) | METAP1ACHEPARP10PARP1MAOA | |
| SCHEMBL30933590 | 0.78 | METAP1 (0.41) | METAP1ACHEPARP10PARP1ADORA1 | |
| SCHEMBL9629516 | 0.78 | METAP1 (0.41) | METAP1ACHEPARP10PARP1ADORA1 | |
| SCHEMBL28115385 | 0.75 | METAP1 (0.39) | METAP1ACHEPARP10PARP1ADORA1 | |
| SCHEMBL8344964 | 0.72 | METAP1 (0.53) | METAP1ACHEPARP10PARP1ADORA1 | |
| SCHEMBL17073935 | 0.69 | HTR6 (0.40) | ACHEMAOAMAOBCYP2A6MAPT | |
| SCHEMBL20219239 | 0.68 | HTR7 (0.39) | METAP1ACHEPARP10PARP1ADORA1 | |
| SCHEMBL11768880 | 0.68 | HTR7 (0.49) | METAP1ACHEPARP10PARP1ADORA1 | |
| SCHEMBL29633503 | 0.67 | METAP1 (0.57) | METAP1ACHEPARP10PARP1ADORA1 | |
| SCHEMBL546147 | 0.67 | METAP1 (0.57) | METAP1ACHEPARP10PARP1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349150-A | Method for synthesizing indene (1,2-b) indole-10(5H)-ketone compounds | 河南师范大学 | 2017-01-25 | — | — | CN | disclosed |