SCHEMBL28115430

SCHEMBL28115430

C12C3C4C5C1[Fe]23451678C2C1C6C7C28.CC(=O)Nc1ccccc1B(O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.49
HPGD P15428 1/20 0.49
POLB P06746 2/20 0.44
CYP2C19 P33261 2/20 0.44
MAPK1 P28482 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HTT P42858 1/20 0.41
LMNA P02545 1/20 0.41
MAOA P21397 1/20 0.41
NAPRT Q6XQN6 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
RXFP1 Q9HBX9 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL521100 0.89 ALDH1A1 (0.59) ALDH1A1HPGDPOLBCYP2C19MAPK1
SCHEMBL29469169 0.89 ALDH1A1 (0.59) ALDH1A1HPGDPOLBCYP2C19MAPK1
SCHEMBL9945927 0.79 ALDH1A1 (0.55) ALDH1A1HPGDPOLBCYP2C19MAPK1
SCHEMBL29953619 0.75 GAA (0.53) ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10
SCHEMBL4780965 0.75 GAA (0.53) ALDH1A1HPGDTSHRSMN1; SMN2HSD17B10
SCHEMBL3149525 0.74 RAB9A (0.45) ALDH1A1HPGDPOLBCYP2C19NPC1
SCHEMBL56441 0.74 GAA (0.50) ALDH1A1HPGDPOLBNPC1RAB9A
SCHEMBL2549708 0.74 ALDH1A1 (0.53) ALDH1A1HPGDPOLBCYP2C19MAPK1
SCHEMBL3792891 0.74 ALDH1A1 (0.48) ALDH1A1HPGDPOLBCYP2C19MAPK1
SCHEMBL6689158 0.73 ALDH1A1 (0.74) ALDH1A1HPGDPOLBCYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103823071-B \" magnetic bead glycolated hemoglobin ferrocene boric acid \" complex and application thereof 北京怡成生物电子技术股份有限公司 2016-12-21 CN disclosed