Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521100 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL29469169 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL28115430 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL6689158 | 0.79 | ALDH1A1 (0.74) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL2549708 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL16187648 | 0.76 | KEAP1 (0.49) | ALDH1A1HPGDSMN1; SMN2TSHRHTT | |
| SCHEMBL3792891 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL3585917 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL3242695 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1HPGDPOLBCYP2C19MAOA | |
| SCHEMBL6326388 | 0.73 | ALDH1A1 (0.65) | ALDH1A1HPGDPOLBCYP2C19MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885HPGD 2142/4885POLB 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.