Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252872 | 0.89 | HIF1A (0.51) | RIPK1HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL21523774 | 0.87 | HIF1A (0.47) | RIPK1HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL21523675 | 0.85 | SCD5 (0.45) | RIPK1HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL21523602 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL21198961 | 0.82 | ALKBH1 (0.42) | RIPK1HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL21523770 | 0.80 | LMNA (0.58) | HIF1AMEN1KMT2AALDH1A1HTT | |
| SCHEMBL21523794 | 0.78 | KMT2A (0.58) | MEN1KMT2AALDH1A1HTTMAPT | |
| SCHEMBL23388368 | 0.75 | F2 (0.43) | RIPK1HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL28837321 | 0.75 | RIPK1 (0.75) | RIPK1HIF1AMEN1KMT2AALDH1A1 | |
| SCHEMBL21523639 | 0.75 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669558-B | Benzyl -1H- pyrazoles, benzyl -1H- azole derivatives and its preparation method and application | 四川大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |