Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 10/20 | 0.58 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607699 | 0.84 | NOD1 (0.65) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL28116715 | 0.78 | ALDH3A1 (0.55) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL28309197 | 0.77 | ALDH3A1 (0.72) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL5201003 | 0.76 | NOD1 (0.57) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL14247143 | 0.74 | NOD1 (1.00) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL28116287 | 0.72 | NPC1 (0.59) | NOD1ALDH1A1HSD17B10LMNASRC | |
| SCHEMBL14356320 | 0.71 | NOD1 (0.67) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL573404 | 0.71 | KDM4E (0.53) | NOD1CXCL8GAAALDH3A1ALDH1A1 | |
| SCHEMBL15294556 | 0.71 | NOD1 (0.61) | NOD1CXCL8NOD2GAAALDH3A1 | |
| SCHEMBL28116275 | 0.70 | ALDH1A1 (0.71) | GAAALDH3A1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | claimed |
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |