Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CXCL8 | P10145 | 3/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607699 | 0.80 | NOD1 (0.65) | ALDH3A1LMNACXCL8NOD1GAA | |
| SCHEMBL427783 | 0.80 | TUBB4A (0.55) | ALDH3A1TSHRCXCL8NOD1HPGD | |
| SCHEMBL28116655 | 0.78 | NOD1 (0.58) | ALDH3A1LMNATSHRCXCL8NOD1 | |
| SCHEMBL16689153 | 0.77 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2TSHRMEN1MAPT | |
| SCHEMBL8023358 | 0.76 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2TSHRMAPTGAA | |
| SCHEMBL28309197 | 0.76 | ALDH3A1 (0.72) | ALDH3A1LMNAMEN1KMT2ACXCL8 | |
| SCHEMBL28144747 | 0.75 | NOD1 (0.66) | ALDH3A1LMNASMN1; SMN2TSHRMAPT | |
| SCHEMBL18040304 | 0.74 | MAPT (0.54) | LMNASMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL28116285 | 0.74 | CNR2 (0.63) | LMNASMN1; SMN2TSHRMEN1MAPT | |
| SCHEMBL8021582 | 0.73 | ALDH1A1 (0.67) | ALDH3A1LMNASMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |