Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391109 | 0.84 | KMT2A (0.48) | LMNAMAPK1TDP1ALOX5TSHR | |
| SCHEMBL8710773 | 0.84 | MAPT (0.53) | KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL8876872 | 0.82 | SMN1; SMN2 (0.54) | LMNAMAPK1ALOX5NPSR1KMT2A | |
| SCHEMBL13244348 | 0.82 | NCEH1 (0.56) | LMNAMAPK1TDP1ALOX5TSHR | |
| SCHEMBL1252851 | 0.79 | KMT2A (0.63) | LMNAMAPK1TDP1ALOX5TSHR | |
| SCHEMBL15413796 | 0.79 | MAPK1 (0.50) | LMNAMAPK1TDP1ALOX5TSHR | |
| SCHEMBL4813457 | 0.79 | ALDH1A1 (0.51) | LMNAMAPK1TDP1ALOX5TSHR | |
| SCHEMBL15414250 | 0.79 | ALOX5 (0.51) | LMNAMAPK1TDP1ALOX5TSHR | |
| SCHEMBL10588542 | 0.78 | ALOX5 (0.47) | LMNAMAPK1TDP1ALOX5TSHR | |
| SCHEMBL8270789 | 0.78 | LMNA (0.49) | LMNAMAPK1TDP1ALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803882-B | Compound and preparation method and application thereof | 江西同和药业股份有限公司 | 2017-02-01 | — | — | CN | disclosed |