Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.52 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116865 | 0.82 | LMNA (0.47) | SMN1; SMN2RAB9AMAPTLMNAKMT2A | |
| SCHEMBL8876988 | 0.80 | NPC1 (0.57) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL8710773 | 0.78 | MAPT (0.53) | SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL5113336 | 0.77 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL24953210 | 0.75 | HSD17B10 (0.63) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL31573987 | 0.75 | KMT2A (0.48) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL31573991 | 0.75 | KMT2A (0.48) | SMN1; SMN2NPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL8406800 | 0.75 | MAPK1 (0.47) | SMN1; SMN2RAB9AMAPTL3MBTL1LMNA | |
| SCHEMBL6036331 | 0.75 | MAPK1 (0.51) | NPC1RAB9AMAPTL3MBTL1LMNA | |
| SCHEMBL7743971 | 0.75 | RXRA (0.48) | MAPTL3MBTL1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594016-A | ANTIDIABETIC AGENTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0604983-B1 | Naphthalene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-11-20 | — | — | EP | disclosed |
| EP-0604983-A1 | Naphthalene derivatives | Mitsubishi Chemical Corporation (JP) | 1994-07-06 | — | — | EP | disclosed |