Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28200405 | 0.95 | TGM2 (0.58) | TGM2KMT2AZDHHC20ZDHHC2GAA | |
| Phenol SCHEMBL27863161 | 0.95 | TGM2 (0.58) | TGM2KMT2AZDHHC20ZDHHC2GAA | |
| Phenol SCHEMBL27470656 | 0.83 | TGM2 (0.48) | TGM2KMT2AALDH1A1LMNAMMP1 | |
| SCHEMBL36683 | 0.82 | — | — | |
| SCHEMBL1065204 | 0.82 | ZDHHC20 (0.61) | TGM2ZDHHC20ZDHHC2HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28790272 | 0.80 | ZDHHC20 (0.59) | TGM2KMT2AZDHHC20ZDHHC2HTT | |
| Phenol SCHEMBL27944565 | 0.78 | TGM2 (0.47) | TGM2KMT2AZDHHC20ZDHHC2ALDH1A1 | |
| Phenol SCHEMBL28345445 | 0.77 | MMP1 (0.60) | TGM2KMT2AALDH1A1LMNAGAA | |
| SCHEMBL6209769 | 0.77 | TAAR1 (0.69) | TGM2KMT2AHTTALDH1A1LMNA | |
| SCHEMBL155436 | 0.77 | ZDHHC20 (0.64) | TGM2ZDHHC20ZDHHC2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102753564-B | 6-substituted estradiol derivatives and methods of use thereof | 安德斯有限责任公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-101594874-B | 6-alkoxyalkyl estradiol derivative and application | 安德斯有限责任公司 | 2017-02-08 | — | — | CN | disclosed |