SCHEMBL28117894

SCHEMBL28117894

O=C1CCC(=O)N1c1ccc(Br)cc1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.58
MGLL Q99685 1/20 0.58
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA9 Q16790 2/20 0.55
POLB P06746 1/20 0.55
CA2 P00918 1/20 0.53
KMT2A Q03164 4/20 0.52
LMNA P02545 3/20 0.50
GLA P06280 1/20 0.48
HSP90AA1 P07900 1/20 0.45
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
ATM Q13315 1/20 0.43
MMP13 P45452 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31637511 0.91 KMT2A (0.64) FAAHMGLLCA12CA1CA9
SCHEMBL11478927 0.87 CA12 (0.67) FAAHMGLLCA12CA1CA9
SCHEMBL9692622 0.80 POLB (0.46) CA12CA1CA9POLBCA2
SCHEMBL9819285 0.77 FAAH (0.44) FAAHMGLLCA12CA1CA9
SCHEMBL28503117 0.76 FAAH (0.58) FAAHMGLLCA12CA1CA9
SCHEMBL11883244 0.76 L3MBTL1 (0.44) MGLLCA12CA1CA9POLB
SCHEMBL1949985 0.76 LMNA (0.64) MGLLCA12CA1CA9POLB
SCHEMBL572883 0.76 KMT2A (0.83) MGLLCA12CA1CA9POLB
SCHEMBL6140745 0.76 CA12 (0.59) CA12CA1CA9POLBCA2
SCHEMBL3780616 0.76 LMNA (0.67) MGLLCA12CA1CA9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111960975-B Allyl thioether compound and preparation method thereof 盐城工学院 2022-05-06 CN disclosed
CN-111960975-A Allyl thioether compound and preparation method thereof 盐城工学院 2020-11-20 CN disclosed
CN-106397445-B Pyrazoles N- p-bromophenyl maleimide derivatives containing chromone structure and preparation method and application 绍兴文理学院 2018-05-29 CN disclosed
CN-106397445-A Pyrazoles N-p-bromophenyl maleimide derivative containing chromone structure as well as preparation method and application thereof 绍兴文理学院 2017-02-15 CN disclosed