Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819362 | 0.84 | ELANE (0.59) | MGLLPOLBALDH1A1F2ELANE | |
| SCHEMBL9819453 | 0.83 | ALDH1A1 (0.49) | MGLLPOLBALDH1A1ELANEL3MBTL1 | |
| SCHEMBL6366715 | 0.82 | POLB (0.46) | MGLLPOLBALDH1A1L3MBTL1GAA | |
| SCHEMBL28117894 | 0.77 | FAAH (0.58) | FAAHMGLLHSP90AA1POLBALDH1A1 | |
| SCHEMBL9819508 | 0.76 | KMT2A (0.50) | ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL31637511 | 0.74 | KMT2A (0.64) | FAAHMGLLHSP90AA1POLBALDH1A1 | |
| SCHEMBL19297530 | 0.73 | RAB9A (0.45) | FAAHMGLLPOLBBRD4CTSG | |
| SCHEMBL9819370 | 0.72 | KMT2A (0.53) | MGLLHSP90AA1ALDH1A1L3MBTL1GAA | |
| SCHEMBL19707200 | 0.71 | FAAH (0.50) | FAAHMGLLHSP90AA1POLBALDH1A1 | |
| SCHEMBL4733957 | 0.70 | IDO1 (0.50) | FAAHMGLLALDH1A1CTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |