Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987454 | 0.80 | AR (0.45) | ARSIRT6MEN1CYP1A2CYP3A4 | |
| SCHEMBL6990671 | 0.79 | AR (0.41) | ARSIRT6MEN1CYP1A2CYP3A4 | |
| SCHEMBL28872810 | 0.77 | HTR6 (0.42) | SIRT6HTR2C | |
| SCHEMBL11093931 | 0.77 | SIRT6 (0.60) | ARSIRT6MEN1CYP1A2CYP3A4 | |
| SCHEMBL28118767 | 0.76 | AR (0.39) | ARSIRT6MEN1CYP1A2CYP3A4 | |
| SCHEMBL28291525 | 0.72 | AR (0.42) | ARMEN1KMT2APIK3CDPIK3CA | |
| SCHEMBL16879321 | 0.72 | AR (0.65) | ARMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1191623 | 0.71 | AR (0.68) | ARMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28088572 | 0.71 | AR (0.33) | ARNR1H2NR1H3CYP3A4PIK3CD | |
| SCHEMBL25316229 | 0.67 | PIK3CD (0.43) | ARCYP2C9PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573921-B | Imidazolidine-2, 4-dione derivatives | 博福-益普生（天津）制药有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-106573921-A | Novel imidazolidine-2, 4-dione derivatives | 博福-益普生（天津）制药有限公司 | 2017-04-19 | — | — | CN | disclosed |