Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CBX7 | O95931 | 2/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.41 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.41 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837904 | 0.88 | NQO2 (0.47) | NQO2IDO1GSK3BMEN1KMT2A | |
| SCHEMBL28837811 | 0.83 | NQO2 (0.47) | NQO2IDO1GSK3BCBX7CDYL | |
| SCHEMBL28118909 | 0.82 | NQO2 (0.46) | NQO2IDO1GSK3BCBX7CDYL | |
| SCHEMBL28118828 | 0.80 | KIF11 (0.48) | NQO2GSK3B | |
| SCHEMBL28119211 | 0.79 | IDO1 (0.47) | NQO2IDO1GSK3BCBX7CDYL | |
| SCHEMBL28119198 | 0.71 | NQO2 (0.47) | NQO2IDO1GSK3BCBX7CDYL | |
| SCHEMBL28305518 | 0.71 | MEN1 (0.33) | MEN1KMT2AP2RX3PGR | |
| SCHEMBL28119197 | 0.71 | NQO2 (0.46) | NQO2IDO1GSK3BMEN1KMT2A | |
| SCHEMBL28118834 | 0.69 | NQO2 (0.46) | NQO2IDO1CDYLCDYL2MEN1 | |
| SCHEMBL28118833 | 0.67 | ATM (0.47) | NQO2IDO1GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316923-A | Disubstituted indol-2(1H)-one derivative and preparation method and application thereof | 中南大学 | 2017-01-11 | — | — | CN | claimed |
| CN-106316923-A | Disubstituted indol-2(1H)-one derivative and preparation method and application thereof | 中南大学 | 2017-01-11 | — | — | CN | disclosed |