Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CBX7 | O95931 | 2/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.42 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.42 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | UNG | P13051 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837811 | 0.99 | NQO2 (0.47) | NQO2IDO1CBX7CDYLCDYL2 | |
| SCHEMBL28119197 | 0.88 | NQO2 (0.46) | NQO2IDO1GSK3BMEN1KMT2A | |
| SCHEMBL28119198 | 0.87 | NQO2 (0.47) | NQO2IDO1CBX7CDYLCDYL2 | |
| SCHEMBL28118836 | 0.82 | NQO2 (0.47) | NQO2IDO1CBX7CDYLCDYL2 | |
| SCHEMBL28118830 | 0.81 | KIF11 (0.47) | NQO2MEN1KMT2AHTR7LMNA | |
| SCHEMBL28119235 | 0.79 | KIF11 (0.48) | NQO2MEN1KMT2AHTR7LMNA | |
| SCHEMBL28119211 | 0.78 | IDO1 (0.47) | NQO2IDO1CBX7CDYLCDYL2 | |
| SCHEMBL28305520 | 0.72 | MEN1 (0.33) | MEN1KMT2ALMNAMAPT | |
| SCHEMBL250063 | 0.71 | GAA (0.54) | IDO1MEN1KMT2AUSP2HPGD | |
| SCHEMBL28837904 | 0.71 | NQO2 (0.47) | NQO2IDO1GSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316923-A | Disubstituted indol-2(1H)-one derivative and preparation method and application thereof | 中南大学 | 2017-01-11 | — | — | CN | claimed |
| CN-106316923-A | Disubstituted indol-2(1H)-one derivative and preparation method and application thereof | 中南大学 | 2017-01-11 | — | — | CN | disclosed |