Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086292 | 0.84 | MAPT (0.57) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL7560417 | 0.83 | L3MBTL1 (0.66) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL5217880 | 0.83 | MAPT (0.63) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL29291321 | 0.83 | MAPT (0.56) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL4483081 | 0.82 | TDP1 (0.61) | CES2CES1NPSR1ALDH1A1LMNA | |
| SCHEMBL4604321 | 0.81 | MAPT (0.61) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL29262742 | 0.81 | LMNA (0.67) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL812736 | 0.81 | LMNA (0.67) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL4604318 | 0.81 | MAPT (0.61) | MAPTNPC1RAB9APOLBMEN1 | |
| SCHEMBL28398882 | 0.81 | CES2 (0.52) | MAPTNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106348990-B | A method of synthesis 1,2,2- triaryl ethyl ketone and its derivative | 兰州大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-106348990-A | Method for synthesizing 1,2,2-triaryl ethyl ketone and derivatives thereof | 兰州大学 | 2017-01-25 | — | — | CN | disclosed |