Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 1/20 | 0.53 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.53 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27248419 | 0.77 | HTR2A (0.45) | KCNJ6KCNJ5KCNJ3POLBMAPT | |
| SCHEMBL11684952 | 0.76 | HSD11B1 (0.65) | KCNJ6KCNJ5KCNJ3POLBKMT2A | |
| SCHEMBL6868006 | 0.76 | MTOR (0.46) | KCNJ6KCNJ5KCNJ3HPGDMTOR | |
| SCHEMBL2303216 | 0.72 | LMNA (0.63) | KCNJ6KCNJ5KCNJ3MAPTTP53 | |
| SCHEMBL28922109 | 0.71 | CA12 (0.52) | HPGDPOLBALDH1A1 | |
| SCHEMBL701463 | 0.70 | ALDH1A1 (0.55) | KCNJ6KCNJ5KCNJ3POLBMAPT | |
| Fenuron SCHEMBL9451054 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ANAPRTHSD17B10 | |
| Fenuron SCHEMBL10806698 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ANAPRTHSD17B10 | |
| Fenuron SCHEMBL8366971 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ANAPRTHSD17B10 | |
| Fenuron SCHEMBL62004 | 0.70 | TSHR (0.64) | MTORMEN1KMT2ANAPRTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458940-A | Inhibitors of human immunodeficiency virus replication | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | disclosed |