Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814446 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TSHRPTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL559558 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A1PTGS1PTGS2SMN1; SMN2NPC1 | |
| SCHEMBL3716769 | 0.70 | ALDH1A1 (0.48) | ALDH1A1TSHRPTGS2LMNAHPGD | |
| SCHEMBL29952946 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAKMT2AMAPT | |
| SCHEMBL1532661 | 0.69 | ALDH1A1 (0.60) | ALDH1A1TSHRSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL16955594 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TSHRPTGS2LMNAHPGD | |
| SCHEMBL3409591 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAKMT2AMAPT | |
| SCHEMBL19879746 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNACYP1A2KMT2A | |
| SCHEMBL154107 | 0.67 | ALDH1A1 (0.40) | ALDH1A1TSHRPTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL9442667 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TSHRLMNACYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458904-A | N-substituted sulfonamide compound and method for producing same | 宇部兴产株式会社 | 2017-02-22 | — | — | CN | disclosed |