Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710124 | 0.81 | CYP3A4 (0.48) | LTA4HPARP15PARP10TDP1SLC6A3 | |
| SCHEMBL28752735 | 0.81 | EPHX2 (0.50) | LTA4HLMNASLC6A3 | |
| SCHEMBL765420 | 0.81 | SLC6A3 (0.51) | LTA4HTDP1RAB9ANPC1LMNA | |
| SCHEMBL9389496 | 0.80 | SLC6A3 (0.49) | LTA4HTDP1LMNASLC6A3 | |
| SCHEMBL24768074 | 0.77 | SLC6A3 (0.55) | LTA4HRAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL9257429 | 0.77 | HRH3 (0.49) | LTA4HCYP19A1 | |
| SCHEMBL10824593 | 0.73 | TBXAS1 (0.57) | ESR1ESR2LTA4HRAB9ANPC1 | |
| SCHEMBL10824595 | 0.73 | TBXAS1 (0.57) | ESR1ESR2LTA4HRAB9ANPC1 | |
| SCHEMBL28150474 | 0.69 | ALDH1A1 (0.47) | RAB9ASLC6A3CYP3A4 | |
| SCHEMBL2969737 | 0.68 | ESR1 (1.00) | ESR1ESR2LTA4HTDP1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503856-B | A kind of chromone substituted tetrahydrothiazole dione compounds and its application for treating diabetes medicament | 重庆理工大学 | 2018-03-09 | — | — | CN | claimed |
| CN-1603323-A | Process for preparing 5-[[4-[2-(5- ethyl-2- pyridyl) ethoxy] phenyl] methyl]-2,4- thiazolidinedione | SHANDONG A & T PHARM CO LTD (CN) | 2005-04-06 | — | — | CN | claimed |
| CN-105503856-B | A kind of chromone substituted tetrahydrothiazole dione compounds and its application for treating diabetes medicament | 重庆理工大学 | 2018-03-09 | — | — | CN | disclosed |
| CN-104522003-B | Multifunctional biological agent used for crop acarid killing and deinsectization and preparation method and application thereof | 何水德 | 2017-01-25 | — | — | CN | disclosed |
| CN-1603323-A | Process for preparing 5-[[4-[2-(5- ethyl-2- pyridyl) ethoxy] phenyl] methyl]-2,4- thiazolidinedione | SHANDONG A & T PHARM CO LTD (CN) | 2005-04-06 | — | — | CN | disclosed |