SCHEMBL28127449

SCHEMBL28127449

CC(O)C(C)Cc1ccccc1CN

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.40
DPP4 P27487 2/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
TRPA1 O75762 2/20 0.37
CYP2D6 P10635 1/20 0.36
TAAR1 Q96RJ0 5/20 0.34
SLC6A2 P23975 2/20 0.34
MAOA P21397 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
KDM4E B2RXH2 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27787183 0.80 SLC6A2 (0.54) PNMTTAAR1SLC6A2MAOASLC6A4
SCHEMBL13994811 0.80 GABRA1 (0.52) PNMTDPP4GABRA1GABRB2TAAR1
Ammonia Solution, Strong SCHEMBL28293881 0.78 GABRA1 (0.50) PNMTDPP4GABRA1GABRB2TAAR1
Hydrochloric Acid SCHEMBL4599374 0.78 GABRA1 (0.50) PNMTDPP4GABRA1GABRB2TAAR1
SCHEMBL30735652 0.77 TAAR1 (0.43) GABRA1GABRB2TRPA1CYP2D6TAAR1
SCHEMBL110971 0.77 TAAR1 (0.43) GABRA1GABRB2TRPA1CYP2D6TAAR1
SCHEMBL10781796 0.75 PNMT (0.40) PNMTDPP4TAAR1SLC6A2MAOA
SCHEMBL21777255 0.75 TAAR1 (0.47) GABRA1GABRB2TRPA1CYP2D6TAAR1
SCHEMBL8985113 0.75 APAF1 (0.51) CYP2D6KDM4ESMN1; SMN2
Methylamine SCHEMBL28339099 0.74 PNMT (0.57) PNMTDPP4TAAR1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661498-A Isomer mixtures of unsaturated macrocyclic musk compounds 西姆莱斯有限公司 2017-05-10 CN disclosed
CN-106535866-A Mixtures having enriched E-isomers of unsaturated macrocyclic musk compounds 西姆莱斯有限公司 2017-03-22 CN disclosed