Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3728598 | 0.82 | IDO1 (0.47) | IDO1TDO2KMT2ASMN1; SMN2CHEK2 | |
| SCHEMBL28276191 | 0.81 | KDM4E (0.42) | IRAK4IDO1TDO2KMT2ASMN1; SMN2 | |
| SCHEMBL8828571 | 0.79 | IDO1 (0.41) | IDO1TDO2KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8380942 | 0.79 | IRAK4 (0.49) | IRAK4KMT2ACTNNB1BCAT2ALDH1A1 | |
| SCHEMBL6266294 | 0.77 | IRAK4 (0.47) | IRAK4KMT2APARP1CTNNB1BCAT2 | |
| SCHEMBL28477237 | 0.77 | IRAK4 (0.47) | IRAK4KMT2ACTNNB1BCAT2ALDH1A1 | |
| SCHEMBL3663651 | 0.77 | IRAK4 (0.47) | IRAK4KMT2APARP1CTNNB1BCAT2 | |
| SCHEMBL4114971 | 0.77 | IRAK4 (0.51) | IRAK4KMT2ASMN1; SMN2PARP1CTNNB1 | |
| SCHEMBL5968855 | 0.77 | IRAK4 (0.47) | IRAK4KMT2APARP1CTNNB1BCAT2 | |
| SCHEMBL4458402 | 0.77 | ALDH1A1 (0.58) | IRAK4KMT2APARP1CTNNB1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543048-B | A kind of new 3- methoxybenzyls-benzamides adjusts the compound and its medical usage of estrogen-related receptor activity | 齐鲁工业大学 | 2018-05-22 | — | — | CN | disclosed |
| CN-106551921-A | A kind of new compound and its medical usage that methoxybenzyl benzamideses are adjusted with estrogen-related receptor activity | 齐鲁工业大学 | 2017-04-05 | — | — | CN | disclosed |
| CN-106543048-A | A kind of new 3 methoxybenzyl benzamides adjusts the compound and its medical usage of estrogen-related receptor activity | 齐鲁工业大学 | 2017-03-29 | — | — | CN | disclosed |
| CN-106543048-A | A kind of new 3 methoxybenzyl benzamides adjusts the compound and its medical usage of estrogen-related receptor activity | 齐鲁工业大学 | 2017-03-29 | — | — | CN | disclosed |