Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.36 |
| ▸ | TDO2 | P48775 | 4/20 | 0.36 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132011 | 0.81 | IRAK4 (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL858 | 0.75 | CYP2D6 (0.42) | KDM4ETSHRLMNACYP2D6SRC | |
| SCHEMBL4458402 | 0.74 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTHPGDTSHR | |
| Hydrochloric Acid SCHEMBL10708013 | 0.73 | HTT (0.44) | KDM4ETSHRLMNACYP2D6IDO1 | |
| SCHEMBL3831520 | 0.73 | BCAT2 (0.46) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL4192923 | 0.73 | BCAT2 (0.46) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL5504292 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1LMNACYP2D6NPSR1 | |
| SCHEMBL22032854 | 0.71 | BCAT2 (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL6266294 | 0.71 | IRAK4 (0.47) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3663651 | 0.71 | IRAK4 (0.47) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110042099-A | RNA in skin and fibrotic conditions is interfered | 菲奥医药公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-105131067-B | RNA in skin and fibrotic conditions is interfered | 雷克西制药公司 | 2019-02-19 | — | — | CN | disclosed |