Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480094 | 0.79 | LMNA (0.48) | LMNAMAPK1HTTSMN1; SMN2HTR6 | |
| SCHEMBL17099790 | 0.79 | LMNA (0.48) | LMNAMAPK1HTTSMN1; SMN2HTR6 | |
| SCHEMBL5088679 | 0.77 | DRD2 (0.36) | HTR6DRD2DRD1DRD4DRD5 | |
| SCHEMBL8585353 | 0.77 | NR1H3 (0.39) | LMNADRD2MEN1ALDH1A1HPGD | |
| SCHEMBL8222700 | 0.75 | SCN9A (0.39) | DRD2DRD3HPGD | |
| SCHEMBL3133132 | 0.75 | ACHE (0.36) | MAPK1DRD2DRD1DRD4DRD5 | |
| SCHEMBL15712827 | 0.75 | PLAU (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29213977 | 0.74 | PTPN1 (0.42) | — | |
| SCHEMBL1056365 | 0.74 | ALDH1A1 (0.46) | MAPK1HTTL3MBTL1DRD2DRD1 | |
| SCHEMBL29937164 | 0.74 | ALDH1A1 (0.46) | MAPK1HTTL3MBTL1DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483335-A | Amyloid protein targeting agent and its application method | AMYDIS INC | 2019-11-22 | — | — | CN | disclosed |
| CN-106573880-B | Amyloid targeting agents and methods of use thereof | 阿米达斯公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-106573880-A | Amyloid targeting agents and methods of use thereof | 阿米达斯诊断公司 | 2017-04-19 | — | — | CN | disclosed |