Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088679 | 0.85 | DRD2 (0.36) | ACHECYP1A2DRD2DRD4DRD3 | |
| SCHEMBL8222700 | 0.82 | SCN9A (0.39) | ACHEDRD2DRD3 | |
| SCHEMBL13233215 | 0.82 | NCEH1 (0.48) | KMT2ARXFP1ALPLERN1NCEH1 | |
| SCHEMBL6704839 | 0.82 | NCEH1 (0.39) | KMT2ARXFP1CA1CA2ALPL | |
| SCHEMBL15712827 | 0.82 | PLAU (0.46) | CA1CA2DRD2DRD4DRD3 | |
| SCHEMBL29213977 | 0.81 | PTPN1 (0.42) | CA1CA2CA9PDE4APDE4C | |
| SCHEMBL29937164 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AMAPK1CA1CA2 | |
| SCHEMBL1056365 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AMAPK1CA1CA2 | |
| SCHEMBL6473030 | 0.80 | DRD2 (0.37) | CA1CA2DRD2DRD4DRD3 | |
| SCHEMBL1180547 | 0.80 | MTNR1A (0.44) | ACHECYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483335-A | Amyloid protein targeting agent and its application method | AMYDIS INC | 2019-11-22 | — | — | CN | disclosed |
| CN-106573880-B | Amyloid targeting agents and methods of use thereof | 阿米达斯公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-106573880-A | Amyloid targeting agents and methods of use thereof | 阿米达斯诊断公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-102574828-A | Fluoranthene compound and organic electroluminescent element using same | IDEMITSU KOSAN CO | 2012-07-11 | — | — | CN | disclosed |
| CN-102209722-A | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO | 2011-10-05 | — | — | CN | disclosed |
| EP-1993986-B1 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2010-07-14 | — | — | EP | disclosed |
| US-20100010265-A1 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | COMELY ALEXANDER CHRISTIAN | 2010-01-14 | — | — | US | disclosed |
| US-7645910-B2 | Process for the preparation of aromatic derivatives of 1-adamantane | FINORGA SAS (FR) | 2010-01-12 | — | — | US | disclosed |
| US-20090137841-A1 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | FINORGA SAS (FR) | 2009-05-28 | — | — | US | disclosed |
| CN-1265645-A | Urokinase inhibitors | ABBOTT LAB (US) | 2000-09-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010265-A1 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | AMD1, CYP51A1, DDC | ACHE 646/4885MEN1 2401/4885KMT2A 4095/4885 |
| US-20090137841-A1 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE | AMD1, CYP51A1, DDC | ACHE 646/4885MEN1 2401/4885KMT2A 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.