Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926937 | 0.70 | HTR5A (0.35) | — | |
| SCHEMBL16410556 | 0.68 | BACE1 (0.35) | BACE1 | |
| SCHEMBL14586408 | 0.64 | BACE1 (0.33) | BACE1ALDH1A1 | |
| SCHEMBL9445185 | 0.62 | TERT (0.38) | ALDH1A1 | |
| SCHEMBL3648624 | 0.60 | HTR5A (0.36) | — | |
| SCHEMBL24618514 | 0.60 | AKR1B1 (0.36) | BACE1ALDH1A1 | |
| SCHEMBL10819304 | 0.60 | HCAR3 (0.36) | BACE1ALDH1A1HCAR3HCAR2 | |
| SCHEMBL21082996 | 0.59 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL25242834 | 0.59 | PDK2 (0.42) | — | |
| SCHEMBL25294070 | 0.59 | PDK2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458913-A | Antidiabetic tricyclic compounds | 默沙东公司 | 2017-02-22 | — | — | CN | disclosed |