Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645900 | 0.84 | CYP2C9 (0.37) | PAOXCHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL27872670 | 0.81 | ACHE (0.38) | ACHE | |
| SCHEMBL28137724 | 0.78 | KDM4E (0.37) | KDM4EMEN1KMT2ALMNANPSR1 | |
| SCHEMBL28860189 | 0.77 | CA12 (0.36) | PAOXKDM4EMEN1KMT2ALMNA | |
| SCHEMBL28244485 | 0.72 | GAA (0.37) | KDM4EPOLBACHE | |
| SCHEMBL27766308 | 0.72 | ACHE (0.35) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL21016721 | 0.72 | ACHE (0.42) | KDM4EMEN1KMT2AACHESMN1; SMN2 | |
| Bicarbonate SCHEMBL30077224 | 0.71 | PAOX (0.50) | PAOXKDM4EMEN1KMT2ASLC22A1 | |
| SCHEMBL27993979 | 0.71 | SAT1 (0.41) | MEN1KMT2ASMN1; SMN2CYP2D6 | |
| SCHEMBL25595752 | 0.71 | CHRNB2 (0.50) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1917873-A | Diurea derivatives | ACTIVE BIOTECH AB (SE) | 2007-02-21 | — | — | CN | disclosed |