Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38660069 | 1.00 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9ANPC1AHRFYN | |
| SCHEMBL11546092 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2RAB9ANPC1AHRMTNR1A | |
| SCHEMBL10264545 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9ANPC1AHRMEN1 | |
| SCHEMBL13978380 | 0.84 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1AHRMTNR1A | |
| SCHEMBL5357024 | 0.84 | LMNA (0.54) | SMN1; SMN2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL14026887 | 0.84 | HTT (0.63) | SMN1; SMN2RAB9ANPC1AHRMEN1 | |
| SCHEMBL10755249 | 0.83 | NPC1 (0.74) | SMN1; SMN2RAB9ANPC1AHRMTNR1A | |
| SCHEMBL4727210 | 0.83 | KMT2A (0.67) | SMN1; SMN2RAB9ANPC1AHRMTNR1A | |
| SCHEMBL9504353 | 0.83 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1AHRMTNR1A | |
| SCHEMBL29875454 | 0.82 | MTNR1A (0.79) | SMN1; SMN2RAB9ANPC1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660991-A | Antiproliferative compounds and methods of use thereof | 细胞基因公司 | 2017-05-10 | — | — | CN | disclosed |