Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 4/20 | 0.51 |
| ▸ | HTR6 | P50406 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | APEH | P13798 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | PARL | Q9H300 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641128 | 0.83 | RAPGEF4 (0.61) | ALDH1A1LMNAHTTL3MBTL1MMP2 | |
| SCHEMBL1599348 | 0.76 | HTR6 (0.50) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL1599343 | 0.76 | HTR6 (0.50) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL28189646 | 0.76 | HTR6 (0.50) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL14760380 | 0.76 | HTR6 (0.50) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL29713729 | 0.76 | PPME1 (0.55) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL10176180 | 0.73 | HTR6 (0.47) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL17900455 | 0.73 | PPME1 (0.49) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL16469258 | 0.73 | ALDH1A1 (0.48) | PPME1HTR6MEN1ALDH1A1LMNA | |
| SCHEMBL1616366 | 0.73 | PPME1 (0.60) | PPME1HTR6MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103497188-B | The compound of regulation c fms and/or c kit activity and its application | 普莱希科公司 | 2017-06-23 | — | — | CN | disclosed |