Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPME1 | Q9Y570 | 2/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | APEH | P13798 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | PARL | Q9H300 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28058142 | 0.80 | PPME1 (0.48) | ALDH1A1HTR6MEN1LMNAHPGD | |
| SCHEMBL28189646 | 0.77 | HTR6 (0.50) | ALDH1A1HSD17B10TDP1HTR6MEN1 | |
| SCHEMBL27662268 | 0.74 | PPME1 (0.49) | ALDH1A1HTR6MEN1LMNAHPGD | |
| SCHEMBL28139909 | 0.73 | PPME1 (0.51) | ALDH1A1HTR6MEN1LMNAHPGD | |
| SCHEMBL1599348 | 0.73 | HTR6 (0.50) | ALDH1A1HTR6MEN1LMNAHPGD | |
| SCHEMBL14760380 | 0.73 | HTR6 (0.50) | ALDH1A1HTR6MEN1LMNAHPGD | |
| SCHEMBL1599343 | 0.73 | HTR6 (0.50) | ALDH1A1HTR6MEN1LMNAHPGD | |
| SCHEMBL30317840 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1HTR6MEN1 | |
| SCHEMBL10176180 | 0.70 | HTR6 (0.47) | ALDH1A1HTR6MEN1LMNAHPGD | |
| SCHEMBL17900455 | 0.70 | PPME1 (0.49) | ALDH1A1TDP1HTR6MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459296-B2 | Antibacterial compounds | Infex Therapeutics Limited (GB) | 2022-10-04 | — | — | US | disclosed |
| US-20210230115-A1 | Antibacterial Compounds | Infex Therapeutics Limited (GB) | 2021-07-29 | — | — | US | disclosed |
| US-9533985-B2 | Sulfonamide derivative and medicinal use thereof | EA PHARMA CO., LTD. (JP) | 2017-01-03 | — | — | US | disclosed |
| US-9533985-B2 | Sulfonamide derivative and medicinal use thereof | EA PHARMA CO., LTD. (JP) | 2017-01-03 | — | — | US | disclosed |
| EP-2842945-B1 | SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | EA PHARMA CO LTD (JP) | 2016-10-26 | — | — | EP | disclosed |
| EP-2842945-A1 | SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2015-03-04 | — | — | EP | disclosed |
| CN-104395297-A | Sulfonamide derivatives and pharmaceutical use thereof | AJINOMOTO KK | 2015-03-04 | — | — | CN | disclosed |
| US-20150051395-A1 | SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | AJINOMOTO CO., LTD. (JP) | 2015-02-19 | — | — | US | disclosed |
| US-20150051395-A1 | SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | AJINOMOTO CO., LTD. (JP) | 2015-02-19 | — | — | US | disclosed |
| US-20150051395-A1 | SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | AJINOMOTO CO., LTD. (JP) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230115-A1 | Antibacterial Compounds | GAA, MGAM, NQO1 | ALDH1A1 291/4885HSD17B10 308/4885TDP1 4465/4885 |
| US-11459296-B2 | Antibacterial compounds | GAA, MGAM, NQO1 | ALDH1A1 291/4885HSD17B10 308/4885TDP1 4465/4885 |
| US-20150051395-A1 | SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | ITGB4, ITGA4, ITGA2 | ALDH1A1 1151/4885HSD17B10 4530/4885TDP1 4743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.