Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.33 |
| ▸ | FLT4 | P35916 | 3/20 | 0.33 |
| ▸ | KDR | P35968 | 3/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28140899 | 0.81 | CXCR2 (0.33) | FLT1FLT4KDR | |
| SCHEMBL28253353 | 0.77 | ALOX15 (0.33) | — | |
| SCHEMBL103521 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL17094979 | 0.69 | HSD17B10 (0.43) | FLT1FLT4KDR | |
| SCHEMBL9517136 | 0.69 | FLT1 (0.43) | FLT1FLT4KDR | |
| SCHEMBL9197331 | 0.69 | ALDH1A1 (0.45) | — | |
| SCHEMBL28174295 | 0.68 | CA1 (0.33) | FLT1FLT4KDR | |
| SCHEMBL1552127 | 0.67 | ALDH1A1 (0.43) | — | |
| SCHEMBL27799698 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL27294789 | 0.67 | ALDH1A1 (0.47) | FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104119310-B | N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors, and medical compositions containing same | 约翰斯霍普金斯大学 | 2017-04-12 | — | — | CN | disclosed |