Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 18/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28146207 | 0.84 | RBP4 (0.48) | RBP4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17223054 | 0.83 | RBP4 (0.52) | RBP4 | |
| SCHEMBL29915715 | 0.83 | RBP4 (0.52) | RBP4 | |
| SCHEMBL28146200 | 0.81 | RBP4 (0.50) | RBP4 | |
| SCHEMBL28146205 | 0.80 | RBP4 (0.48) | RBP4CYP3A4CYP2C9SLC9A1CYP2C19 | |
| SCHEMBL17224429 | 0.79 | RBP4 (0.53) | RBP4CYP3A4CYP2C9SLC9A1CYP2C19 | |
| SCHEMBL17232804 | 0.78 | RBP4 (0.52) | RBP4CYP3A4CYP2C9SLC9A1CYP2C19 | |
| SCHEMBL28787308 | 0.76 | DRD4 (0.42) | CYP3A4CYP2C9SLC9A1CYP2C19KCNH2 | |
| SCHEMBL28844206 | 0.76 | RBP4 (0.46) | RBP4SLC9A1 | |
| SCHEMBL28024911 | 0.75 | GPR119 (0.40) | CYP3A4CYP2C9SLC9A1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106794364-A | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2017-05-31 | — | — | CN | disclosed |