Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTR1E | P28566 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815633 | 0.98 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3047350 | 0.97 | PGR (0.43) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1769324 | 0.93 | PGR (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5475184 | 0.87 | SCD (0.42) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3897910 | 0.85 | L3MBTL1 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2PGR | |
| SCHEMBL2876866 | 0.85 | PDE4A (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL521393 | 0.85 | ADRB1 (0.44) | PGRSCDOPRM1 | |
| SCHEMBL2814607 | 0.81 | KDM1A (0.49) | ALDH1A1KMT2APGRLMNAPOLB | |
| SCHEMBL10574972 | 0.79 | MEN1 (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL24992890 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASCDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098592-A1 | PREPARATION METHOD FOR CARBON-LOADED IRON-BASED CATALYST AND USE THEREOF IN SYNTHESIS OF INTERMEDIATES OF ANTI-CANCER INHIBITORS | 奥锐特药业股份有限公司 | 2023-06-08 | — | — | WO | claimed |
| CN-112441941-B | Preparation method of 1- (4-aminophenyl) cyclopentyl formonitrile | 浙江荣耀生物科技股份有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114315595-A | Preparation method of carbon-supported iron-based catalyst and synthesis application of anti-cancer inhibitor intermediate thereof | 湖南大学 | 2022-04-12 | — | — | CN | claimed |
| CN-112441941-A | Preparation method of 1- (4-aminophenyl) cyclopentyl formonitrile | 浙江荣耀生物科技股份有限公司 | 2021-03-05 | — | — | CN | claimed |
| CN-121949152-A | Hydrogenation reduction preparation process of apatinib intermediate | 山东省科学院菏泽分院 | 2026-05-01 | — | — | CN | disclosed |
| CN-114315595-B | Preparation method of carbon-supported iron-based catalyst and application of intermediate synthesis of anticancer inhibitor of carbon-supported iron-based catalyst | 奥锐特药业股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-11673857-B2 | Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile | Zhejiang Rongyao Biotech CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| US-11673857-B2 | Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile | Zhejiang Rongyao Biotech CO., LTD. (CN) | 2023-06-13 | — | — | US | disclosed |
| WO-2023098592-A1 | PREPARATION METHOD FOR CARBON-LOADED IRON-BASED CATALYST AND USE THEREOF IN SYNTHESIS OF INTERMEDIATES OF ANTI-CANCER INHIBITORS | 奥锐特药业股份有限公司 | 2023-06-08 | — | — | WO | disclosed |
| CN-112441941-B | Preparation method of 1- (4-aminophenyl) cyclopentyl formonitrile | 浙江荣耀生物科技股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-112441941-B | Preparation method of 1- (4-aminophenyl) cyclopentyl formonitrile | 浙江荣耀生物科技股份有限公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20220177420-A1 | PREPARATION METHOD OF 1-(4-AMINOPHENYL)CYCLOPENTANECARBONITRILE | Zhejiang Rongyao Biotech CO., LTD. (CN) | 2022-06-09 | — | — | US | disclosed |
| US-20070249608-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
| US-20070249608-A1 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-10-25 | — | — | US | disclosed |
| EP-0474733-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC UREA COMPOUNDS | WARNER LAMBERT CO (US) | 1994-08-31 | — | — | EP | disclosed |
| EP-0474733-A1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC UREA COMPOUNDS. | WARNER LAMBERT CO (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5015644-A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | WARNER-LAMBERT COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| WO-1990015048-A1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC UREA COMPOUNDS | WARNER-LAMBERT COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249608-A1 | INHIBITORS OF C-FMS KINASE | MUSK, FRK, FES | ALDH1A1 4702/4885MEN1 740/4885KMT2A 844/4885 |
| US-11673857-B2 | Preparation method of 1-(4-aminophenyl)cyclopentanecarbonitrile | CPNE4, CPN1, DCUN1D4 | ALDH1A1 442/4885MEN1 3471/4885KMT2A 1312/4885 |
| US-20220177420-A1 | PREPARATION METHOD OF 1-(4-AMINOPHENYL)CYCLOPENTANECARBONITRILE | CPNE4, CPN1, DCUN1D4 | ALDH1A1 442/4885MEN1 3471/4885KMT2A 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.