Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27913877 | 0.87 | PROKR1 (0.37) | GPR119OPRL1MAOAHCRTR2 | |
| SCHEMBL28787308 | 0.86 | DRD4 (0.42) | GPR119OPRL1SLC9A1CYP3A4CYP2C9 | |
| SCHEMBL28024448 | 0.86 | OPRL1 (0.36) | OPRL1SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27948292 | 0.85 | SLC9A1 (0.48) | SLC9A1CYP3A4CYP2C9CYP2C19KCNH2 | |
| SCHEMBL28839896 | 0.84 | NR1H2 (0.34) | GPR119SLC9A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27790080 | 0.82 | RBP4 (0.46) | GPR119OPRL1SLC9A1CYP3A4CYP2C9 | |
| SCHEMBL6395680 | 0.81 | GPR119 (0.56) | GPR119NR1H2SMN1; SMN2 | |
| SCHEMBL29535803 | 0.81 | GPR119 (0.56) | GPR119NR1H2SMN1; SMN2 | |
| SCHEMBL15530574 | 0.80 | HTR1D (0.39) | OPRL1MAOAHTR1DHTR1BGRM2 | |
| SCHEMBL27682015 | 0.80 | RIPK1 (0.39) | PARP10CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837835-A | VEGFR3 inhibitors | CANCER THERAPEUTICS CRC PTY LTD | 2015-08-12 | — | — | CN | disclosed |