Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733419 | 0.81 | NCF1 (0.74) | NCF1MAPTHTTMETAP1POLB | |
| SCHEMBL25722018 | 0.76 | SMN1; SMN2 (0.53) | MAPTHTTMETAP1POLBMAPK10 | |
| SCHEMBL30308898 | 0.76 | SMN1; SMN2 (0.53) | MAPTHTTMETAP1POLBMAPK10 | |
| SCHEMBL2541848 | 0.75 | KDM4E (0.60) | NCF1MAPTPOLBCYP1A2MEN1 | |
| SCHEMBL23755331 | 0.74 | PIK3CA (0.47) | NCF1MAPTPOLBCYP1A2CYP2D6 | |
| SCHEMBL24776296 | 0.71 | MAPT (0.47) | NCF1MAPTMETAP1POLBCYP1A2 | |
| SCHEMBL31283928 | 0.71 | MAPT (0.47) | NCF1MAPTMETAP1POLBCYP1A2 | |
| SCHEMBL25390232 | 0.70 | PIK3CA (0.55) | NCF1MAPTCYP1A2CYP2D6KMT2A | |
| SCHEMBL27272600 | 0.70 | ALDH1A1 (0.50) | MAPTHTTMETAP1POLBMAPK10 | |
| SCHEMBL25719380 | 0.70 | ALDH1A1 (0.50) | MAPTHTTMETAP1POLBMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037765-A2 | 4-MORPHOLINO-PYRIDO[3,2-D]PYRIMIDINES | MERCK SERONO S.A. (CH) | 2010-04-08 | — | — | WO | disclosed |