Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852341 | 0.95 | TRPA1 (0.48) | TRPA1SMN1; SMN2MAPK1TSHRLMNA | |
| SCHEMBL8540223 | 0.93 | TRPA1 (0.47) | TRPA1SMN1; SMN2MAPK1TSHRLMNA | |
| SCHEMBL8540221 | 0.93 | TRPA1 (0.47) | TRPA1SMN1; SMN2MAPK1TSHRLMNA | |
| SCHEMBL2296429 | 0.83 | TSHR (0.45) | MAPK1TSHRLMNAALDH1A1ATM | |
| SCHEMBL28217526 | 0.83 | SLC18A3 (0.36) | TRPA1ALDH1A1 | |
| SCHEMBL13330544 | 0.82 | CHRNB2 (0.55) | LMNAMAPTALDH1A1 | |
| SCHEMBL28148132 | 0.82 | PDE2A (0.40) | TRPA1TSHR | |
| SCHEMBL28167653 | 0.81 | RIPK1 (0.54) | TSHRLMNAMAPT | |
| SCHEMBL30824575 | 0.81 | RIPK1 (0.54) | TSHRLMNAMAPT | |
| SCHEMBL4158117 | 0.79 | ALDH1A1 (0.42) | TRPA1MAPK1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968371-A | Novel PRMT5 inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-106817900-A | Novel naphthyridines and isoquinolin and its purposes as CDK8/19 inhibitor | 默克专利有限公司 | 2017-06-09 | — | — | CN | disclosed |