Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824575 | 1.00 | RIPK1 (0.54) | RIPK1TSHRJAK2NTRK1MAOA | |
| SCHEMBL28168148 | 0.82 | SIGMAR1 (0.44) | — | |
| SCHEMBL27851907 | 0.81 | RIPK1 (0.42) | RIPK1TSHRMAOAMAOBMAPT | |
| SCHEMBL28149189 | 0.81 | TRPA1 (0.53) | TSHRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL28938994 | 0.81 | ALDH1A1 (0.47) | RIPK1MAOAMAOBKMT2AMAPT | |
| SCHEMBL13330544 | 0.80 | CHRNB2 (0.55) | RIPK1KMT2ALMNAMAPT | |
| SCHEMBL2336871 | 0.79 | RIPK1 (0.40) | RIPK1TSHRMAOAMAOB | |
| SCHEMBL28168305 | 0.78 | DRD2 (0.48) | KMT2A | |
| SCHEMBL22754932 | 0.78 | OPRM1 (0.41) | OPRM1OPRD1 | |
| SCHEMBL20705955 | 0.77 | ALDH1A1 (0.56) | RIPK1TSHRJAK2NTRK1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108492-B | Cell necrosis inhibitor | 北京生命科学研究所 | 2021-03-19 | — | — | CN | disclosed |
| CN-107108492-A | Inhibitor of cellular necrosis | 北京生命科学研究所 | 2017-08-29 | — | — | CN | disclosed |