SCHEMBL28150596

SCHEMBL28150596

CCC[Si](OC)(OC)OCNS(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.41
LMNA P02545 2/20 0.41
KDM4E B2RXH2 2/20 0.41
KEAP1 Q14145 1/20 0.41
PKM P14618 1/20 0.41
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.39
POLB P06746 1/20 0.39
GBA1 P04062 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17077606 0.77 MAPK1 (0.59) ALDH1A1TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL14150586 0.75 MAPK1 (0.65) ALDH1A1TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL574791 0.74 MAPK1 (0.64) ALDH1A1TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL143915 0.74 MAPT (0.36) ALDH1A1LMNAPKMMAPTNPSR1
SCHEMBL29669045 0.70 ALDH1A1 (0.56) ALDH1A1TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL14150232 0.70 ALDH1A1 (0.58) ALDH1A1TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL7350215 0.69 MAPK1 (0.66) ALDH1A1TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL301798 0.69 ALDH1A1 (0.68) ALDH1A1TSHRMAPK1SMN1; SMN2LMNA
SCHEMBL17893514 0.69 MEN1 (0.49) LMNAKDM4EMAPTTDP1
SCHEMBL28157614 0.69 PSIP1 (0.36) ALDH1A1TSHRSMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103718111-B The photoetching film-forming composition of titaniferous and silicon 日产化学工业株式会社 2017-06-23 CN disclosed