SCHEMBL143915

SCHEMBL143915

CCC[Si](OC)(OC)OCNc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
ALDH1A1 P00352 2/20 0.34
KCNH3 Q9ULD8 3/20 0.33
KMT2A Q03164 2/20 0.33
GRM5 P41594 1/20 0.33
HPGD P15428 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
PKM P14618 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.31
ADRA2A P08913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28089433 0.86 MAPT (0.38) MAPTALDH1A1KCNH3KMT2AGRM5
Diphenylamine SCHEMBL28718278 0.79 HSD17B10 (0.46) MAPTALDH1A1KCNH3KMT2AHPGD
SCHEMBL28650710 0.79 MAPT (0.50) MAPTALDH1A1KCNH3KMT2AL3MBTL1
SCHEMBL11444038 0.78 MAPT (0.34) MAPTALDH1A1KCNH3KMT2AGRM5
SCHEMBL814026 0.77 KCNH3 (0.41) MAPTALDH1A1KCNH3KMT2ATAAR1
SCHEMBL4616628 0.75 MAPT (0.40) MAPTALDH1A1KCNH3KMT2ATAAR1
SCHEMBL1069533 0.75 MAPT (0.40) MAPTALDH1A1KCNH3KMT2ATAAR1
SCHEMBL28197378 0.74 MAPT (0.48) MAPTALDH1A1KCNH3L3MBTL1NPSR1
SCHEMBL28150596 0.74 ALDH1A1 (0.46) MAPTALDH1A1PKMNPSR1LMNA
SCHEMBL17893514 0.74 MEN1 (0.49) MAPTKMT2AMAOAMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116376287-A Preparation method of silicone rubber for intelligent lock 重庆亿如电子有限公司 2023-07-04 CN claimed
CN-111890767-A Ultrathin polyethylene microporous breathable film and preparation method thereof 湖北宏裕新型包材股份有限公司 2020-11-06 CN claimed
CN-111646766-A Slope protection material and maintenance method thereof 山东安澜工程建设有限公司 2020-09-11 CN claimed
US-10196349-B2 Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2019-02-05 US claimed
CN-108559440-A A kind of no-solvent type polyurethane laminating adhesive and its preparation method and application of high speed compound, rapid aging 上海回天新材料有限公司 2018-09-21 CN claimed
EP-2823009-B1 EPOXY SILOXANE COATING COMPOSITIONS PPG IND OHIO INC (US) 2017-05-03 EP claimed
US-9267006-B2 Temperature controlled sol-gel co-condensation NOVAN, INC. (US) 2016-02-23 US claimed
US-9187501-B2 Nitric oxide-releasing nanorods and their methods of use THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2015-11-17 US claimed
US-20150141606-A1 TEMPERATURE CONTROLLED SOL-GEL CO-CONDENSATION LIGAND PHARMACEUTICALS INCORPORATED 2015-05-21 US claimed
US-20140134321-A1 NITRIC OXIDE-RELEASING COATINGS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2014-05-15 US claimed
US-20140065200-A1 NITRIC OXIDE-RELEASING NANORODS AND THEIR METHODS OF USE THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2014-03-06 US claimed
EP-2488591-A1 NITRIC OXIDE-RELEASING COATINGS Novan, Inc. (US) 2012-08-22 EP claimed
US-20120059116-A1 METHOD OF PRODUCING PHENOLATE ESTER COMPOUNDS NANO-X GMBH (DE) 2012-03-08 US claimed
WO-2011047013-A1 NITRIC OXIDE-RELEASING COATINGS NOVAN, INC. (US) 2011-04-21 WO claimed
US-20110086234-A1 NITRIC OXIDE-RELEASING COATINGS NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR 2011-04-14 US claimed
US-5089464-A Release agent is oxyalkylene oligomer modified by a silane coupling agent NISSHINBO INDUSTRIES, INC. (JP) 1992-02-18 US claimed
EP-3758679-B1 NITRIC OXIDE RELEASING SUPPOSITORIES AND METHODS OF USE THEREOF LIGAND PHARM INC (US) 2026-05-06 EP disclosed
US-12503428-B2 Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2025-12-23 US disclosed
US-6406783-B1 Bulk absorber and process for manufacturing same MCDONNELL DOUGLAS HELICOPTER, CO. 2002-06-18 US disclosed
US-20020061432-A1 Proton conductive film and fuel cell using the same KABUSHIKI KAISHA TOSHIBA (JP) 2002-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503428-B2 Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures NOS2, NOS3, NOS1 MAPT 4512/4885ALDH1A1 2777/4885KCNH3 1688/4885
US-20140065200-A1 NITRIC OXIDE-RELEASING NANORODS AND THEIR METHODS OF USE NOS2, NOS1, NOS3 MAPT 2848/4885ALDH1A1 957/4885KCNH3 4685/4885
US-10196349-B2 Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures NOS2, NOS3, NOS1 MAPT 4512/4885ALDH1A1 2777/4885KCNH3 1688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.