Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | HPGDS | O60760 | 3/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23247441 | 0.90 | OPRD1 (0.44) | OPRD1USP30HPGDSPRMT5HCRTR1 | |
| SCHEMBL18845574 | 0.86 | OPRD1 (0.55) | OPRD1USP30HPGDSHCRTR1HCRTR2 | |
| SCHEMBL8601591 | 0.86 | MAPK14 (0.55) | — | |
| SCHEMBL8602866 | 0.84 | USP30 (0.45) | USP30HCRTR1HCRTR2MEN1ALDH1A1 | |
| SCHEMBL14479516 | 0.80 | OPRD1 (0.43) | OPRD1USP30HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL11982069 | 0.80 | OPRD1 (0.43) | OPRD1USP30HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL12632942 | 0.80 | CYP3A4 (0.46) | USP30HCRTR1HCRTR2MEN1ALDH1A1 | |
| SCHEMBL23247964 | 0.80 | RAB9A (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL28152181 | 0.80 | RAB9A (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL18731202 | 0.79 | UCHL1 (0.43) | USP30HCRTR1HCRTR2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928126-B | Amide derivative, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2019-12-20 | — | — | CN | disclosed |
| CN-106928126-A | A kind of amide derivatives and preparation method thereof and application pharmaceutically | 四川海思科制药有限公司 | 2017-07-07 | — | — | CN | disclosed |