Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibenzofuran SCHEMBL28107446 | 0.85 | KDM4E (0.52) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| Dibenzofuran SCHEMBL27974583 | 0.83 | KDM4E (0.50) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| Dibenzofuran SCHEMBL28992416 | 0.82 | CYP1A2 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1CYP1A2 | |
| Dibenzofuran SCHEMBL11090130 | 0.75 | GPR84 (0.55) | SMN1; SMN2NPC1RAB9APTPN1ALDH1A1 | |
| Dibenzofuran SCHEMBL8207 | 0.75 | MAPT (0.68) | SMN1; SMN2NPC1RAB9AALDH1A1CYP3A4 | |
| Dibenzofuran SCHEMBL9868133 | 0.75 | MAPT (0.68) | SMN1; SMN2NPC1RAB9AALDH1A1CYP3A4 | |
| Dibenzofuran SCHEMBL29635704 | 0.75 | MAPT (0.68) | SMN1; SMN2NPC1RAB9AALDH1A1CYP3A4 | |
| SCHEMBL10338681 | 0.73 | LMNA (0.54) | SMN1; SMN2LMNAALDH1A1HSD17B10TSHR | |
| Naphthalene SCHEMBL27493313 | 0.73 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9ALMNAHTT | |
| SCHEMBL24307195 | 0.72 | MAPT (0.65) | SMN1; SMN2NPC1RAB9AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106928172-B | A kind of process for refining of dibenzofuran | 辽宁科技学院 | 2019-03-26 | — | — | CN | disclosed |
| CN-106928172-A | A kind of process for refining of dibenzofuran | 辽宁科技学院 | 2017-07-07 | — | — | CN | disclosed |