SCHEMBL2815501

SCHEMBL2815501

CCOCCOc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 6/20 0.44
KDM4E B2RXH2 4/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
L3MBTL1 Q9Y468 4/20 0.36
NOS3 P29474 3/20 0.36
NOS1 P29475 3/20 0.36
NOS2 P35228 3/20 0.36
MEN1 O00255 3/20 0.36
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 3/20 0.36
NPSR1 Q6W5P4 1/20 0.34
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
MAPK14 Q16539 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7149339 0.93 NCF1 (0.42) NCF1KDM4ESMN1; SMN2L3MBTL1MEN1
SCHEMBL990306 0.88 CNR1 (0.43) KDM4ESMN1; SMN2L3MBTL1NOS3NOS1
SCHEMBL29366362 0.88 L3MBTL1 (0.43) KDM4ESMN1; SMN2L3MBTL1NOS3NOS1
SCHEMBL268758 0.88 L3MBTL1 (0.43) KDM4ESMN1; SMN2L3MBTL1NOS3NOS1
SCHEMBL392406 0.87 CNR1 (0.44) L3MBTL1NOS3NOS1NOS2MEN1
SCHEMBL29402318 0.87 CNR1 (0.44) L3MBTL1NOS3NOS1NOS2MEN1
SCHEMBL15476088 0.84 NOS3 (0.37) SMN1; SMN2L3MBTL1NOS3NOS1NOS2
SCHEMBL267070 0.81 MYC (0.35) NCF1L3MBTL1MAPK14
SCHEMBL29860074 0.81 MYC (0.35) NCF1L3MBTL1MAPK14
SCHEMBL15475516 0.81 EGFR (0.34) L3MBTL1NOS3NOS1NOS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4189323-A Radiation-sensitive copying composition HOECHST AKTIENGESELLSCHAFT (DE) 1980-02-19 US claimed
US-8404402-B2 Photopolymerisable system for hologram formation SONY DADC AUSTRIA AG (AT) 2013-03-26 US disclosed
US-20100248088-A1 PHOTOPOLYMERISABLE SYSTEM FOR HOLOGRAM FORMATION SONY DADC AUSTRIA AG (AT) 2010-09-30 US disclosed
EP-2233976-A1 Photopolymerisable system for hologram formation Sony DADC Austria AG (AT) 2010-09-29 EP disclosed
EP-1426793-B1 Photodefinable composition including a silsesquioxane polymer and an optical waveguide formed therefrom SHIPLEY CO LLC (US) 2009-02-25 EP disclosed
US-7024093-B2 Methods of forming waveguides and waveguides formed therefrom SHIPLEY COMPANY, LLC (US) 2006-04-04 US disclosed
US-20050180712-A1 PHOTOIMAGEABLE WAVEGUIDE COMPOSITION AND WAVEGUIDE FORMED THEREFROM SHIPLEY COMPANY, L.L.C. (US) 2005-08-18 US disclosed
US-6842577-B2 Photoimageable waveguide composition and waveguide formed therefrom SHIPLEY COMPANY L.L.C. (US) 2005-01-11 US disclosed
US-20040218889-A1 Methods of forming waveguides and waveguides formed therefrom SHIPLEY COMPANY, L.L.C. 2004-11-04 US disclosed
EP-1434068-A2 Methods of forming waveguides that are rounded in cross section and waveguides formed therefrom Shipley Company, L.L.C. (US) 2004-06-30 EP disclosed
US-5070001-A LIGHT-SENSITIVE MIXTURE FOR PRODUCING POSITIVE OR NEGATIVE RELIEF COPIES HOECHST AKTIENGESELLSCHAFT (DE) 1991-12-03 US disclosed
EP-0302359-A2 Positive photo-sensitive compositions HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-08 EP disclosed
US-4789619-A Positive-working radiation-sensitive mixture comprising a sensitizing polymethine dye HOECHST AKTIENGESELLSCHAFT (DE) 1988-12-06 US disclosed
EP-0266654-A2 Light sensitive composition, material containing it and process for producing positive or negative relief copies by using this material HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-11 EP disclosed
EP-0224161-A2 Positive photosensitive composition HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-03 EP disclosed
US-4506006-A Process for preparing relief images in imaged irradiated light-sensitive material having acid-cleavable compound by hot air treatment, overall irradiation and alkaline development HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-19 US disclosed
US-4506003-A Positive-working radiation-sensitive mixture HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-19 US disclosed
US-4250247-A COMPRISING AN ACID-FORMING COMPOUND AND A COMPOUND HAVING AS AN ACID-CLEAVABLE GROUP AN N-ACYLIMINOCARBONATE; RELIEF IMAGES; OFFSET PRINTING HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-10 US disclosed
US-4248957-A ENOL ETHER CONTAINING COMPOUND OF WHICH THE SOLUBILITY IN DEVELOPER INCREASES ON CLEAVAGE HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-03 US disclosed
US-4247611-A ACETAL RESIN, ACID DONER HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-27 US disclosed