SCHEMBL7149339

SCHEMBL7149339

CCOCCOc1cccc2c(-c3nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n3)cccc12

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 11/20 0.42
L3MBTL1 Q9Y468 3/20 0.39
CYBB P04839 1/20 0.36
NOX5 Q96PH1 1/20 0.36
KDM4E B2RXH2 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MAPK14 Q16539 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR1B P28222 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2815501 0.93 NCF1 (0.44) NCF1L3MBTL1KDM4ESMN1; SMN2MAPK14
SCHEMBL990306 0.81 CNR1 (0.43) L3MBTL1KDM4ESMN1; SMN2MEN1ALDH1A1
SCHEMBL29366362 0.80 L3MBTL1 (0.43) L3MBTL1KDM4ESMN1; SMN2MEN1ALDH1A1
SCHEMBL268758 0.80 L3MBTL1 (0.43) L3MBTL1KDM4ESMN1; SMN2MEN1ALDH1A1
SCHEMBL29402318 0.80 CNR1 (0.44) L3MBTL1MEN1KMT2AHTR1B
SCHEMBL392406 0.80 CNR1 (0.44) L3MBTL1MEN1KMT2AHTR1B
SCHEMBL393466 0.78 CYP1A2 (0.40) KDM4ESMN1; SMN2MEN1ALDH1A1KMT2A
SCHEMBL4058163 0.78 NCF1 (0.53) NCF1L3MBTL1CYBBNOX5KDM4E
SCHEMBL267070 0.76 MYC (0.35) NCF1L3MBTL1MAPK14
SCHEMBL15476088 0.76 NOS3 (0.37) L3MBTL1SMN1; SMN2MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1303399-A1 THERMAL DIGITAL LITHOGRAPHIC PRINTING PLATE Kodak Polychrome Graphics Company Ltd. (US) 2003-04-23 EP disclosed
WO-2001096119-A1 THERMAL DIGITAL LITHOGRAPHIC PRINTING PLATE KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2001-12-20 WO disclosed