Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD1 | O60671 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.34 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19050353 | 0.84 | RAD1 (0.40) | RAD1P2RY6BRD4ALDH1A1MEN1 | |
| SCHEMBL3098551 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MEN1MAPTTHRBHPGD | |
| SCHEMBL27484009 | 0.78 | PTGS1 (0.37) | RAD1P2RY6BRD4ALDH1A1MEN1 | |
| SCHEMBL27594155 | 0.78 | RAD1 (0.36) | RAD1P2RY6BRD4ALDH1A1MEN1 | |
| SCHEMBL27519221 | 0.78 | BRD4 (0.49) | RAD1P2RY6BRD4ALDH1A1MEN1 | |
| SCHEMBL31120467 | 0.78 | RAPGEF4 (0.45) | ALDH1A1MEN1APPMAPTTHRB | |
| SCHEMBL18870477 | 0.78 | MPL (0.44) | BRD4ALDH1A1MEN1MAPTHPGD | |
| SCHEMBL11499546 | 0.77 | BRD4 (0.47) | RAD1P2RY6BRD4ALDH1A1MEN1 | |
| SCHEMBL11320660 | 0.76 | HSD17B10 (0.46) | RAD1P2RY6BRD4ALDH1A1MEN1 | |
| SCHEMBL8817406 | 0.74 | SENP2 (0.43) | RAD1P2RY6ALDH1A1MEN1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524055-B | A kind of preparation and application that can distinguish cysteine/homocysteine and glutathione fluorescence probe | 中南大学 | 2018-03-30 | — | — | CN | disclosed |
| CN-106995451-A | A kind of response type cysteine probe and preparation method thereof | 许昌学院 | 2017-08-01 | — | — | CN | disclosed |