Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454674 | 0.83 | HPGDS (0.46) | HPGDSLTA4HADORA2AADORA1HCRTR1 | |
| SCHEMBL9863754 | 0.83 | HPGDS (0.46) | HPGDSLTA4HADORA2AADORA1HCRTR1 | |
| SCHEMBL12648428 | 0.83 | NOTUM (0.50) | HPGDSLTA4HADORA2AADORA1HCRTR1 | |
| SCHEMBL1804513 | 0.83 | PRKCI (0.53) | HPGDSLTA4HCDK8ADORA2AADORA1 | |
| SCHEMBL27594199 | 0.82 | LTA4H (0.50) | HPGDSLOXL2LTA4HLOXADRB2 | |
| SCHEMBL9507339 | 0.82 | HPGDS (0.53) | HPGDSLTA4HADORA2AADORA1HCRTR1 | |
| SCHEMBL3964365 | 0.82 | HPGDS (0.58) | HPGDSLTA4HCDK8 | |
| SCHEMBL6221648 | 0.81 | HPGDS (0.44) | HPGDSLTA4HADORA2AADORA1HCRTR1 | |
| SCHEMBL14983820 | 0.80 | HPGDS (0.43) | HPGDSLTA4HADORA2AADORA1HCRTR1 | |
| SCHEMBL16383003 | 0.80 | HPGDS (0.43) | HPGDSLTA4HADORA2AADORA1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107105655-A | Probe for being imaged Huntington protein | CHDI基金会股份有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-107105655-A | Probe for being imaged Huntington protein | CHDI基金会股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107108534-A | Probes for Imaging Huntingtin | CHDI基金会股份有限公司 | 2017-08-29 | — | — | CN | disclosed |